Weight loss injections have surged in popularity recently, with Ozempic being used by celebrities and Wegovy currently in the process of being approved for use in the UK. However, a new potential weight loss medication called GEP44 has now been developed — and it’s said to not have as many side effects.
Discover all you need to know about GEP44 right here with our full review and see if this weight loss injection is all it claims to be.
What is GEP44?
GEP44 is a new experimental weight loss treatment that has been gaining attention lately. It’s made from a peptide that has been found to promote weight loss without causing nausea, which is a common side effect of other weight loss drugs on the market.
According to recent studies, GEP44 has been shown to reduce body weight and fat mass in animals without causing any adverse effects. Researchers believe that this peptide works by increasing the body’s metabolism, which leads to greater fat-burning and weight loss.
GEP44 is administered via injection, similar to other weight loss drugs like Ozempic and Wegovy.
While GEP44 is still in the experimental stages, many experts are hopeful that it could be an effective weight loss treatment in the future. It’s important to note that GEP44 is still being researched and its safety and effectiveness have not yet been established in humans.
How does GEP44 work?
GEP44 works by activating a specific receptor in the brain known as the melanocortin-4 receptor (MC4R).
MC4R is responsible for regulating your energy levels and metabolism in the body. When activated, it can increase energy expenditure and decrease appetite, leading to weight loss. Researchers believe that GEP44 works by binding to the MC4R receptor and activating it, which in turn helps you to lose weight.
In addition to activating the MC4R receptor, GEP44 may also work by increasing the body’s metabolism, which can help boost weight loss even further. Typically, a slow metabolism can cause weight gain — so increasing it could support you on a weight loss journey.
Does GEP44 have any side effects?
Most weight loss medications or injections tend to have some rather unpleasant side effects.
The most common side effects of other weight loss injections (including Ozempic) are:
- Nausea
- Vomiting
- Diarrhoea
- Bloating
However, with GEP44, this stage of development has shown very few side effects. But it’s important to remember that the studies conducted have been done on animals — not humans.
The studies have suggested that GEP44 can help promote weight loss without causing nausea and other gastrointestinal side effects commonly associated with weight loss drugs. This could be a major advantage over current weight loss medications, which can be difficult for some people to tolerate due to their side effects.
Do any studies back up the weight loss claims?
There have been some promising animal studies that support the weight loss claims for GEP44.
In a study conducted on obese mice, those treated with GEP44 lost significant amounts of body weight and body fat compared to the control group. The treated mice also showed improved glucose tolerance and insulin sensitivity, which are important markers for overall health.
In another study, GEP44 was administered to non-human primates with diet-induced obesity. The treatment was found to significantly reduce body weight and fat mass without causing any significant side effects.
However, as these studies were conducted on animals, further research is needed to determine the safety and effectiveness of GEP44 in humans. Clinical trials involving humans are necessary to fully assess the potential of GEP44 as a weight loss treatment.
What is the difference between Ozempic, Wegovy and GEP44?
Ozempic and Wegovy are medications that are currently approved by the US Food and Drug Administration (FDA) for the treatment of obesity in the US. Whereas, GEP44 is an experimental obesity treatment that is still in the preclinical phase of research.
Ozempic and Wegovy are both injectable medications that contain semaglutide, a synthetic version of the hormone GLP-1. These medications work by regulating blood sugar levels and suppressing appetite, which can lead to weight loss. In clinical trials, both drugs are effective at promoting weight loss and have been approved for use in adults with obesity.
GEP44, on the other hand, is a peptide that works by activating the MC4R. In preclinical studies, GEP44 has been shown to promote weight loss without causing nausea, which is a common side effect of Ozempic and Wegovy.
While Ozempic and Wegovy have already been approved for use in humans and are available in the US, GEP44 is still in the experimental phase of research and has not yet been tested in humans. Therefore, it is not currently available as a treatment option for obesity.
Ozempic is approved for weight loss in the UK, but Wegovy is still in the process of being approved.
To summarise, Ozempic and Wegovy are approved medications that contain semaglutide and are effective at promoting weight loss, while GEP44 is an experimental treatment that works by activating the melanocortin-4 receptor and is still in the preclinical phase of research.
Where can I get GEP44 in the UK?
At the moment, GEP44 is still in the preclinical phase of research, which means it is not yet available as a treatment option for obesity in the UK or anywhere else in the world. Since it has not been approved by regulatory agencies such as the US FDA or the UK’s Medicines and Healthcare Products Regulatory Agency, it is not legally available for use by patients.
It’s important to keep in mind that any medication or treatment that is not approved by regulatory agencies can be dangerous and may have unknown or harmful side effects. Therefore, it’s always best to consult with a doctor before considering any new medication or treatment, especially if it has not been approved for use by regulatory agencies.
So, GEP44 could possibly be the latest weight loss injection to hit the shelves — but it probably won’t be for a while yet. However, preliminary results are looking promising. Hopefully, clinical trials can show the same thing so that it can possibly be approved for aiding weight loss.
Sources
- https://www.medicalnewstoday.com/articles/experimental-obesity-treatment-may-promote-weight-loss-without-nausea
- https://www.acs.org/pressroom/newsreleases/2023/march/obesity-treatment-could-offer-dramatic-weight-loss-without-surgery-or-nausea.html
- https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7956155/
